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Insights, Tools & Tips for People Over 55

Can NAD⁺ Truly Slow Aging? Science-Backed Insights for Healthspan

  • Written by A.G. for Age Well Kit
  • May 20
  • 2 min read

Updated: Sep 15

What You Need to Know Before Trying NAD⁺ to Slow Aging

age-well-kit illustration of older woman in kitchen with supplements, considering NAD+
Let’s take a look at a supplement that may support healthy aging.

Why I am Sharing This


The science around aging is evolving fast, and with it comes a wave of new supplements and claims. One that keeps coming up is NAD⁺, a molecule tied to energy, DNA repair, and the aging process. I had heard about NAD⁺ and the fact that it may slow aging, but I didn’t know much about it, so when this video by SciShow came up in my feed, I watched and it brought a little more clarity.


Here is a short summary of the video and a cheat sheet with the points I found most useful. The video is embedded at the bottom of the page so you can watch it without leaving this site. Below that, you’ll find links to related articles.



Video Summary

This video by SciShow explains what NAD⁺ is, how it supports cellular health, and why its decline with age has become a focus in longevity research. It introduces two supplements (NR and NMN) that may help restore NAD⁺ levels, potentially improving insulin sensitivity, inflammation markers, and overall metabolic function. The video also discusses natural ways to maintain NAD⁺, including exercise and calorie restriction, and critiques the growing wellness trend of costly NAD⁺ infusions. Rather than promising longer life, the focus is on improving healthspan, the years you remain healthy and independent.



Cheat Sheet

Can NAD+ Truly Slow Aging?

Based on the video by SciShow

What Is NAD⁺?

  • NAD⁺ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells.

  • It supports DNA repair, mitochondrial function, and inflammation control.

  • NAD⁺ levels decline with age, which may contribute to fatigue, reduced cell repair, and age-related diseases.


Why Boost NAD⁺?

  • Scientists believe that restoring NAD⁺ levels may help slow cellular aging.

  • It's not about living longer, but about staying healthy longer and extending your healthspan.

How to Boost It:


Supplements (Precursors):
  • NR (Nicotinamide Riboside) and NMN (Nicotinamide Mononucleotide) are easier to absorb than NAD⁺ itself.

  • NR has been shown to raise NAD⁺ levels in older adults without major side effects.

  • NMN improved insulin sensitivity in postmenopausal women with pre-diabetes.

  • A 2022 meta-analysis showed potential benefits for cholesterol and inflammation, though results were modest.


Natural Methods to Boost NAD
  • Regular exercise

  • Calorie restriction and intermittent fasting

  • Avoiding smoking and managing chronic stress


Industry Trends & Cautions

  • NAD⁺ IV drips are promoted in luxury wellness centers and celebrity circles.

  • These treatments are costly and not backed by strong clinical evidence.

  • Supplements are widely available but not regulated by the FDA.


Bottom Line

  • NAD⁺ boosters are promising but still early-stage.

  • Focus first on proven strategies: diet, movement, and stress management.

  • These supplements may support healthy aging, but they’re not a substitute for lifestyle choices.


Disclaimer: This article is for informational purposes only and may include curated or personal content. It is not medical advice. Please consult a licensed provider before making health decisions.

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Video by SciShow. All rights belong to the original creator.


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